Luteolin is an antioxidant flavonoid and a chargeless abolitionist scavenger. It inhibits rat alarmist cytosolic glutathione S-transferase action and soybean and reticulocyte 15-LO (15-lipoxygenases). Luteolin aswell shows cytotoxic furnishings on Raji lymphoma cells. Incubation of the non-tumor corpuscle band C3H10T½CL8 with luteolin after-effects in consecration of p53 accession and apoptosis, with apoptosis occurring at the G2/M appearance of the corpuscle cycle. Luteolin is an inhibitor of Cot, PDE1-5, c-Src, HDAC, Maltase-glucoamylase, Topo I, PKC ε, Fatty Acid Synthase, PPAR γ and MMP.
It has been appropriate that luteolin helps addition the allowed system, promotes advantageous claret glucose levels, and protects the eyes from UV radiation. Studies accept apparent that luteolin is an alive “scavenger” of chargeless radicals, which are molecules and atoms that advance animal tissue and can could cause inflammation, autoimmune disease, and cancer. Luteolin neutralizes chargeless radicals and helps absolute their effects. Luteolin is aswell believed to advice assure the physique adjoin the accident of radiation and chemotherapy.