Loganin (CAS 18524-94-2) Description

Synonym: Loganoside
Application: An iridoid glucoside that inhibits Cox-1 and TNF-α formation
CAS Number: 18524-94-2
Purity: ≥97%
Molecular Weight: 390.38
Molecular Formula: C17H26O10
Solubility: Soluble in water, and 100% ethanol (sparingly). Insoluble in ether, ethyl acetate, and acetone.
Storage: Store at -20° C
Melting Point: 222-223° C
Boiling Point: ~608.77° C at 760 mmHg (Predicted)
Density: ~1.50 g/cm3 (Predicted)
Loganin, an iridoid glucoside, has been appear to be an inhibitor of Cox-1 and aswell acclaimed to abolish TNF-α formation. This admixture aswell has displayed almighty free-radical-scavenging action and inhibitory furnishings on melanogenesis. Research has apparent that Loganin aswell down-regulates mRNA announcement of caspase-3, caspase-9, receptor activator for nuclear agency κ B ligand (RANKL) and up-regulates bcl-2 expression. Experimental studies advance that Loganin can access capacity of osteocalcin and collagen blazon I and aswell advance action of acrid phosphatase.


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